LymphedemaV1, Main, Exploration, bibRecord, 002423

The epidemiology of lymphatic filariasis in Ghana, explained by the possible existence of two strains of Wuchereria bancrofti

Identifieur interne : 002423 ( Main/Exploration ); précédent : 002422; suivant : 002424

The epidemiology of lymphatic filariasis in Ghana, explained by the possible existence of two strains of Wuchereria bancrofti

Auteurs : Dziedzom Komi De Souza [Ghana] ; Jewelna Osei-Poku [Ghana] ; Julia Blum [États-Unis] ; Helena Baidoo [Ghana] ; Charles Addoquaye Brown [Ghana] ; Bernard Walter Lawson [Ghana] ; Michael David Wilson [Ghana] ; Moses John Bockarie ; Daniel Adjei Boakye [Ghana]

Source :

The Pan African Medical Journal [ 1937-8688 ] ; 2014.

RBID : PMC:4218648

Descripteurs français

KwdFr :
- Animaux, Anopheles (parasitologie), Données de séquences moléculaires, Filariose lymphatique (parasitologie), Filariose lymphatique (transmission), Filariose lymphatique (épidémiologie), Ghana (épidémiologie), Humains, Mutation (génétique), Polymorphisme génétique, Prévalence, Vecteurs insectes, Wuchereria bancrofti (génétique).
MESH :
- génétique : Mutation, Wuchereria bancrofti.
- parasitologie : Anopheles, Filariose lymphatique.
- épidémiologie : Filariose lymphatique, Ghana.
- Animaux, Données de séquences moléculaires, Humains, Polymorphisme génétique, Prévalence, Vecteurs insectes.
Wicri :
- geographic : Ghana.

English descriptors

KwdEn :
- Animals, Anopheles (parasitology), Elephantiasis, Filarial (epidemiology), Elephantiasis, Filarial (parasitology), Elephantiasis, Filarial (transmission), Ghana (epidemiology), Humans, Insect Vectors, Molecular Sequence Data, Mutation (genetics), Polymorphism, Genetic, Prevalence, Wuchereria bancrofti (genetics).
MESH :
- geographic , epidemiology : Ghana.
- epidemiology : Elephantiasis, Filarial.
- genetics : Mutation, Wuchereria bancrofti.
- parasitology : Anopheles, Elephantiasis, Filarial.
- transmission : Elephantiasis, Filarial.
- Animals, Humans, Insect Vectors, Molecular Sequence Data, Polymorphism, Genetic, Prevalence.

Abstract

Introduction

Lymphatic filariasis is a debilitating disease caused by the filarial worm Wuchereria bancrofti. It is earmarked for elimination by the year 2020 through the Global Program for the Elimination of LF (GPELF). In Ghana, mass treatment has been on-going since the year 2000. Earlier studies have revealed differing epidemiology of LF in the North and South of Ghana. This study was therefore aimed at understanding the possible impacts of W. bancrofti diversity on the epidemiology and control of LF in Ghana.

Methods

The Mitochondrial, Cytochrome C Oxidase I gene of W. bancrofti samples was sequenced and analyzed. The test sequences were grouped into infrapopulations, and pairwise differences (π) and mutation rates (θ) were computed. The amount of variance within and among populations was also computed using the AMOVA. The evolutionary history was inferred using the Maximum Parsimony method.

Results

Seven samples from the South and 15 samples from the North were sequenced, and submitted to GenBank with accession numbers GQ479497- GQ479518. The results revealed higher mutation frequencies in the southern population, compared to the northern population. Haplotype analyses revealed a total of 11 haplotypes (Hap) in all the 22 DNA sequences, with high genetic variation and polymorphisms within the southern samples.

Conclusion

This study showed that there is considerable genetic variability within W. bancrofti populations in Ghana, differences that might explain the observed epidemiology of LF. Further studies are however required for an in-depth understanding of LF epidemiology and control.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218648

DOI: 10.11604/pamj.2014.17.133.3370
PubMed: 25374638
PubMed Central: 4218648

Affiliations:

Le document en format XML

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<term>Anopheles (parasitology)</term>
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<term>Filariose lymphatique (épidémiologie)</term>
<term>Ghana (épidémiologie)</term>
<term>Humains</term>
<term>Mutation (génétique)</term>
<term>Polymorphisme génétique</term>
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<front><div type="abstract" xml:lang="en"><sec id="st1"><title>Introduction</title>
<p>Lymphatic filariasis is a debilitating disease caused by the filarial worm <italic>Wuchereria bancrofti</italic>
. It is earmarked for elimination by the year 2020 through the Global Program for the Elimination of LF (GPELF). In Ghana, mass treatment has been on-going since the year 2000. Earlier studies have revealed differing epidemiology of LF in the North and South of Ghana. This study was therefore aimed at understanding the possible impacts of <italic>W. bancrofti</italic>
 diversity on the epidemiology and control of LF in Ghana.</p>
</sec>
<sec id="st2"><title>Methods</title>
<p>The Mitochondrial, Cytochrome C Oxidase I gene of <italic>W. bancrofti</italic>
 samples was sequenced and analyzed. The test sequences were grouped into infrapopulations, and pairwise differences (π) and mutation rates (θ) were computed. The amount of variance within and among populations was also computed using the AMOVA. The evolutionary history was inferred using the Maximum Parsimony method.</p>
</sec>
<sec id="st3"><title>Results</title>
<p>Seven samples from the South and 15 samples from the North were sequenced, and submitted to GenBank with accession numbers GQ479497- GQ479518. The results revealed higher mutation frequencies in the southern population, compared to the northern population. Haplotype analyses revealed a total of 11 haplotypes (Hap) in all the 22 DNA sequences, with high genetic variation and polymorphisms within the southern samples.</p>
</sec>
<sec id="st4"><title>Conclusion</title>
<p>This study showed that there is considerable genetic variability within <italic>W. bancrofti</italic>
 populations in Ghana, differences that might explain the observed epidemiology of LF. Further studies are however required for an in-depth understanding of LF epidemiology and control.</p>
</sec>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Zimmerman, Pa" uniqKey="Zimmerman P">PA Zimmerman</name>
</author>
<author><name sortKey="Dadzie, Ky" uniqKey="Dadzie K">KY Dadzie</name>
</author>
<author><name sortKey="De Sole, G" uniqKey="De Sole G">G De Sole</name>
</author>
<author><name sortKey="Remme, J" uniqKey="Remme J">J Remme</name>
</author>
<author><name sortKey="Alley, Es" uniqKey="Alley E">ES Alley</name>
</author>
<author><name sortKey="Unnasch, Tr" uniqKey="Unnasch T">TR Unnasch</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Gyapong, J" uniqKey="Gyapong J">J Gyapong</name>
</author>
<author><name sortKey="Adjei, S" uniqKey="Adjei S">S Adjei</name>
</author>
<author><name sortKey="Sackey, S" uniqKey="Sackey S">S Sackey</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Dunyo, Sk" uniqKey="Dunyo S">SK Dunyo</name>
</author>
<author><name sortKey="Appawu, Ma" uniqKey="Appawu M">MA Appawu</name>
</author>
<author><name sortKey="Nkrumah, Fk" uniqKey="Nkrumah F">FK Nkrumah</name>
</author>
<author><name sortKey="Baffoe Wilmot, A" uniqKey="Baffoe Wilmot A">A Baffoe-Wilmot</name>
</author>
<author><name sortKey="Pedersen, Em" uniqKey="Pedersen E">EM Pedersen</name>
</author>
<author><name sortKey="Simonsen, Pe" uniqKey="Simonsen P">PE Simonsen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kumar, Np" uniqKey="Kumar N">NP Kumar</name>
</author>
<author><name sortKey="Patra, Kp" uniqKey="Patra K">KP Patra</name>
</author>
<author><name sortKey="Hoti, Sl" uniqKey="Hoti S">SL Hoti</name>
</author>
<author><name sortKey="Das, Pk" uniqKey="Das P">PK Das</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Thangadurai, R" uniqKey="Thangadurai R">R Thangadurai</name>
</author>
<author><name sortKey="Hoti, Sl" uniqKey="Hoti S">SL Hoti</name>
</author>
<author><name sortKey="Kumar, Np" uniqKey="Kumar N">NP Kumar</name>
</author>
<author><name sortKey="Das, Pk" uniqKey="Das P">PK Das</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Hebert, Pd" uniqKey="Hebert P">PD Hebert</name>
</author>
<author><name sortKey="Penton, Eh" uniqKey="Penton E">EH Penton</name>
</author>
<author><name sortKey="Burns, Jm" uniqKey="Burns J">JM Burns</name>
</author>
<author><name sortKey="Janzen, Dh" uniqKey="Janzen D">DH Janzen</name>
</author>
<author><name sortKey="Hallwachs, W" uniqKey="Hallwachs W">W Hallwachs</name>
</author>
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Serveur d'exploration sur le lymphœdème

The epidemiology of lymphatic filariasis in Ghana, explained by the possible existence of two strains of Wuchereria bancrofti

The epidemiology of lymphatic filariasis in Ghana, explained by the possible existence of two strains of Wuchereria bancrofti

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	Serveur d'exploration sur le lymphœdème
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